Theoretical and Computational Chemistry are scientific disciplines, which deal with the development and implementation of theoretical approaches in chemistry related problems.Over the past decade, both theoretical and computational chemistry have undergone a paradigm shift triggered by the advent of newer theories/algorithms and high-end supercomputers, making the study of large and complex systems easily within reach. Computational simulations help overcome the inherent limitations of experimental research, and therefore constitute the "third pillar" of science. As a result, there is an explosion in the demand for experts in this field.

Work in Theoretical and Computational Chemistry has also been recognized by the Nobel Committee for Chemistry which awarded the Nobel Prizes to diverse contributions in this field. Theoretical and Computational Chemistry has become essential for the propagation molecular science, and by the end of the 20th century, it would undoubtedly mark the beginning of a new era.

Owing to the practical importance of Theoretical and Computational Chemistry in not just Chemistry and Biochemistry, the Der Pharma Chemica journal has decided to host a special issue highlighting the recent developments and future trends in the fields of Theoretical and Computational Chemistry. The journal would be addressing the following broad topics:

• Drug discovery
• Chemical reaction dynamics
• Protein-protein interaction networks
• Polymer structure and dynamics
• Non-equilibrium statistical mechanics
• Computational and theoretical approaches for biomolecular simulations
• Quantum-mechanical methodologies for energy and electron transport
• Carbon capture and hydrogen storage in porous materials
• Theoretical geochemistry
• Computational modeling of heterogeneous chemistry
• Electronic structure calculations of complexes
• Magnetic and transport properties of metal-organic frameworks

This special issue will hopefully become a stepping stone in Chemistry as well as Biochemistry, and will ultimately result in a better understanding of the world and the laws governing it; not to mention impacts at a much granular level, dedicated to answering questions regarding basic chemical reactions in our day-to-day lives.

Manuscripts highlighting one or more of the above-mentionedfields of study may be submitted to submit@derpharmachemica.com in the form of research article, review articles, case studies, short communications and/or opinion articles.

Green chemistry deals with the development of products and processes, which minimize the generation and use of hazardous substances. Green chemistry aims to prevent pollution by means of synthesis ofnon-toxic chemicals, thereby eliminating exposure to toxic substances. Rather than focusing solely on the toxic or undesirable by-products, green chemistry also encompasses all agents that are part of the process. Furthermore, green chemistry also encourages the use of renewable feedstock, reduction of energy utilization, and optimization of factors beneficial for the environment and human health. Often referred to as pollution prevention at the molecular- level, Green Chemistry is based on twelve cardinal principles that can be harnessed to design or re-design molecules and materials in amuch safer manner.

Over the past decade, green chemistry has evolved and has been adopted across laboratories in both industry and academia. Additionally, novel amendments in chemicals policy have resulted in increased opportunities for legislative action to be taken for protecting human health and the environment. Due to the practical importance of Green chemistry in the development of a more eco-friendly society, the Der Pharma Chemica journal has decided to host a special issue highlighting the applications of Green chemistry. This special issue will be addressing the following topics:

• Green Solvents
• Green Reagents
• Green chemical reactions
• Green Products
• Designs for Energy Efficiency
• Design for Degradation
• Green Manufacture of drugs
• Green Chemistry in agriculture
• Eco-Friendly Dry clean-up of Fabrics
• Green Clean-up of Turbid Water
• Building with Green Technology
• Rainwater Harvesting System
• Insulation of Houses
• Solar Batteries and Water heaters
• Use of Renewable Feedstocks
• Green Technology in Paper and Polymer Industry

This special issue will hopefully impart a much rounded and comprehensive understanding of green chemistry, and would shed light on the various advantages of employing green chemistry in our daily lives. People with an environmentally friendly slant would benefit heavily from the articles published in this issue; others would get exposed to the various pre-existing strategies.

Manuscripts highlighting one or more of the above-mentionedfields of study may be submitted to submit@derpharmachemica.com in the form of research article, review articles, case studies, short communications and/or opinion articles.

Both Medicinal chemistry and Pharmacology deal with the development of affordable therapeutics for human disease. These disciplines span a wide range of drug discovery topics including: green chemical synthesis, in-silico drug design, microbiology, biological testing, toxicity evaluations, pharmacokinetics-pharmacodynamics, and animal model studies.

In the current scenario of evolving viral and bacterial infections, development of novel drugs is the top-priority. Due to the importance of Medicinal chemistry and Pharmacology in the development of more safe and effective drugs, the Der Pharma Chemica journal has decided to host a special issue highlighting the applications of Medicinal chemistry and Pharmacology. 

This special issue is directed at imparting a much comprehensive understanding of drug development. Special emphasis would be placed on the following topics:

• Novel adjuvants designed for improving vaccine efficacy
• Targetting Protease-activated receptors(PAR1)
• Risks associated with new drug development

Manuscripts highlighting one or more of the above-mentioned fields of study may be submitted to submit@derpharmachemica.com in the form of research article, review articles, case studies, short communications and/or opinion articles.

Pharmaceutical chemistry involves the study of drugs and drug development; this includes drug discovery, absorption, metabolism, delivery, and more. Elements of pharmacology, biomedical analysis, pharmacokinetics, and pharmacodynamics are also encompassed in this branch of science.

Over the past decade, Pharmaceutical chemistry has evolved to become the bedrock of the pharmaceutical industry. As Pharmaceutical chemistry plays such a central role in the development of novel and more efficient drugs, the Der Pharma Chemica journal has decided to host a special issue highlighting the applications of Pharmaceutical chemistry. This special issue will be addressing the following topics:

• Structure-based drug design
• Ligand-based analog design
• Pharmacophore based drug design
• 2D and 3D QSAR
• Microwave assisted organic synthesis
• In vitro and in vivo pharmacological evaluation

This special issue will hopefully engender a more comprehensive understanding of the process and challenges associated with drug design and innovation. New innovations and bottlenecks in the field of pharmaceutical chemistry would be at the center of this special issue.

Manuscripts highlighting one or more of the above-mentioned fields of study may be submitted to submit@derpharmachemica.com in the form of research article, review articles, case studies, short communications and/or opinion articles.

Drug discovery and development is usually conducted in a sequential manner, starting with the Discovery and succeeded by the Preclinical, Clinical, and Non-Clinical phases of drug development. The discovery phase is an extremely lengthy and cost-intensive process and is sub-divided into (1) Hit Finding, (2) Lead generation, (3) Lead Optimization, and (4) Candidate Identification Phases. The availability of new drugs amounts to newer and better treatment options for patients. However, innovation in drug development is stalling; the number of drugs approved for every $1 billion invested, has been slashed by 50% every nine years since the 1950s.

A 2013 FDA report suggests that only 40% of the new drug approvals spread over the past 25 years represent genuinely innovative drugs. This “first-in-class” therapeutics has the greatest potential of transforming patient outcomes as they take novel approaches to fight disease. The balance 60%, employ pre-existing approaches, and therefore yields only incremental improvements. Therefore, it is essential to restart the engine of innovation in the field of drug development, the Der Pharma Chemica journal has decided to host a special issue highlighting the latest developments in drug development. The broad subject areas this special issue will be addressing the following topics:

• Precision Medicine
• 3D printing
• mHealth sensors
• Nanotechnology

This special issue hopes to impart a comprehensive understanding of the process of drug development.

Manuscripts highlighting one or more of the above-mentioned fields of study may be submitted to submit@derpharmachemica.com in the form of research article, review articles, case studies, short communications and/or opinion articles.

Organic Chemistry is a very vast topic ranging from organic reactions and compounds to the structural and functional aspects of these compounds. Interdisciplinary aspects of organic chemistry have become increasingly important. Organic and Bio-Molecular chemistry deals with the study of the molecules of life. Therefore, it is essential to understand the basics of organismal biology using the disciplines of organic and biomolecular chemistry, the Der Pharma Chemica journal has decided to host a special issue highlighting the latest developments in Organic and Bio-Molecular chemistry. This special issue will be addressing the following topics:

• Organic synthesis
• Molecular design and structure
• Nanotechnology
• Molecular machines

This special issue hopes to disseminate knowledge regarding all aspects of these crucially important fields.

Manuscripts highlighting one or more of the above-mentioned fields of study may be submitted to submit@derpharmachemica.com in the form of research article, review articles, case studies, short communications and/or opinion articles.

Der Pharma Chemica Journal deals with the diverse scope of the medicinal chemistry, pharmaceutical chemistry, pharmacology and so on. The Journal office has been planning to release the special issue entitled “Formulation and synthesis of Novel anti-microbial, anti-viral and anti-infective drugs” tentatively by the 1^st week of March, 2021. The journal aims to provide the scientific community with the novel and required information regarding the technologies used, parameters considered, specimens analysed, etc. for the future drug discoveries by publishing this special issue.

It is a high time for the pharmaceutical industries to concentrate on the formulation and synthesis of new drugs for combating the emerging chronic Infectious, microbial and viral diseases, as the pandemic is resulting to be the major concern worldwide. In spite of the great advances in drug therapy for treating various infectious, viral, diseases, there is still an urgent need for new and improved drugs due to increasing drug resistance among pathogens, emergence of new pathogens, ease of transmission of infections, ineffective available treatments, toxicity associated with current standard of care, aging populations and the lack of better alternative treatment options. The pharmaceutical industry of today evolved largely from the chemical industry. As these roots would suggest, chemistry was a key component of early drug discoveries that were focused on pain management and the treatment of inflammation and infectious diseases.

The scope of the special issue also targets the below mentioned topics.

• Biofilm
• Bacterial virulence
• Peptide-based drugs
• Anti-parasitic
• Drug screening and  repurposing
• Small molecules and natural products
• Drug Delivery and discovery

Submission Guidelines:

Manuscripts can be submitted through the online submission process on/before February 22, 2021 using the below link: https://www.scholarscentral.org/submissions/der-pharma-chemica.html  

Note: Authors are requested to select the Issue Type as “Special Issue” including mention of the Special issue title while submitting the manuscript. Acknowledgement will be sent within 48 hours of the submission.

• All manuscripts received will undergo a peer review by the Guest Editor.
• Article processing fees for this Special issue is 995 Euros.  
• Authors will be provided with E-print copy of the complete special issue.