Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Youcef Hadef
Department of Pharmacy, Laboratory of Analytical Chemistry, Faculty of Medecine, University Badji Mokhtar, PB 205, 23000, Annaba, AlgeriaPublications
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Research Article
Effect of Ivermectin on the Postpartum Dynamic of Gastrointestinal Strongyles Infection in Traditionally Managed Ewes
Author(s): Ahmed Hadef* and Youcef Hadef
The effect of ivermectin on the dynamic of egg shedding of gastrointestinal strongyles was studied in post-parturient ewes (n=12) from traditionally managed farm located in a north eastern province of Algeria. Fecal samples were collected during the postpartum period to monitor the worm egg count (WEC) before and 3, 22 and 34 days after subcutaneous administration of 0.2 mg/kg of ivermectin. Furthermore, the pretreatment level of ewe’s fat reserve was assessed by the scoring of body condition (BCS) and weighing of body weight (BW) to investigate its effect on ivermectin efficacy. The injection of ivermectin to low infected ewes caused a remove of egg shedding (0 eggs) and a perfect efficacy (100%) in some ewes during the first month post-treatment, mainly on day 3 corresponding to a theoretical time of ivermectin maximal plasmatic concentration. Howe.. Read More»
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