Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Shruti Hirekurubar
Department of pharmaceutical Chemistry, Karnataka State Akkamahadevi Women University Vijayapur, IndiaPublications
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Research Article
Synthesis, Molecular Docking Analysis of New Hetercyclic Scaffolds-Based Quionoline Moiety as Possible Antimicrobial Agents
Author(s): Shruti Hirekurubar and Sanjeev kumar Giri*
In the present work, a general approach for the synthesis of new heterocyclic scaffolds-based quinoline were synthesized. In addition, molecules docking studies were achieved which showed that all the newly synthesized compounds are interacting with active site region of the target enzyme Thymidylate kinase -4QGG, DNA gyrase (PDB ID: 2XCT) Topoisomerase, Dihydrofolate reductase-DHFR- 2w9s, Clumping factor A (ClfA)-1N67 hydrogen bonds and pi-stacked interactions... Read More»
DOI: 10.4172/0975-413X.14.6.7-17
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Citations : 15261
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