Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Saumayata Khobragade
Department of Pharmaceutical Chemistry, Smt Kishoritai Bhoyar College of Pharmacy, New Kamptee (MS)-441002, IndiaPublications
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Research Article
Validated Stability Indicating Method for Estimation of Methoxsalen in Its Formulation By HPLC Analysis
Author(s): Saumayata Khobragade, Apurva Wasnik, Krishna Gupta* and Milind Umekar
Aim: The current study concentrates on the kinetics and behaviour of Methoxsalen in solution state drug degradation. Background: Information from stress testing can subsequently be utilized to create manufacturing procedures or choose the best packaging. It also aids in the preparation of reference data for degradation products that are unknown. Stress testing is frequently repeated as manufacturing techniques, product composition and analytical procedures are modified and brought to a more final condition, even though pre-formulation work is a necessary component of early phase drug development. Objective: The study’s design involves selecting an RP-HPLC method for drug estimation followed by assessments of the kinetics of drug degradation, shelf-life estimation and validation of the method. .. Read More»
DOI: 10.4172/0975-413X.16.4.367-374
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Citations : 15261
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