Papa D Mar

Department of Biology, Faculty of Sciences Ain Chock, Laboratory of Physiopathology, Molecular Genetics and Biotechnology (PGMB), University Hassan II Casablanca, Morocco

Publications

Research Article
Biochemical Study of the Protective Effect of Salvia Officinalis Essential Oil against the Oxidative Stress Induced by Hydrogen Peroxide in Tetrahymena thermophila
Author(s): Papa D Mar, Hatim Otto, Bouchra El khalfi and Abdelaziz Soukri*

In our previous studies, we have illustrated that sage essential oil has a good protective effect against oxidative stress that is induced by hydrogen peroxide on the phenotypic parameters of the protozoan Tetrahymena, given that this protection is characterized by a significant improvement in cell growth and normal cell morphology. On the whole, this work includes studying the intracellular effect of the essential oil of sage on the specific activity of certain antioxidant enzymes such as Catalase (CAT) and Superoxide Dismutase (SOD), lipid peroxidation rate (MDA) and specific activity of the GAPDH biomarker in the model organism Tetrahymena thermophila. As a result, our studies have shown that H2O2 significantly decreases the activities of CAT SOD, GAPDH and significantly increases the rate of MDA. On the other hand, in the presence of sage oil, there is a very significant incre.. Read More»

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