GET THE APP

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

P. Lekhana

Department of Pharmacy, G. Pulla Reddy College of Pharmacy, Mehdipatnam, Hyderabad, Telangana, India

Publications

  • Research Article   
    Quantitative Analysis of Irbesartan in Pharmaceutical Formulation Using MBTH Reagent
    Author(s): Gousia Tazeen, K. Manju Sri, P. Lekhana, Y. Padmavathi and N. Raghavendra Babu*

    A novel, simple, sensitive and efficient method has been established for the quantification of Irbesartan in bulk and pharmaceutical formulations utilizing the MBTH reagent. The objective of this analytical validation approach is to substantiate its efficacy by laboratory trials, demonstrating that the method satisfies the requisite minimal requirements for laboratory application. 3-methyl-2-benzothiazoline hydrazone interacts with the secondary amine group of Irbesartan in the presence of the oxidizing agent cerric ammonium sulphate. The resultant blue chromogen, when analysed spectrophotometrically in the visible spectrum (400 nm-800 nm), exhibits a peak absorbance at 656 nm. This approach can be effectively utilized for quantifying drug content in pharmaceutical formulations. The analysis results have been statistically confirmed. A coefficient of determination (r²) of 0.999 i.. Read More»

    Abstract PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 15261

Der Pharma Chemica received 15261 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry