Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Mohammed Ibrahim
Department of Pharmacy, Southern University Bangladesh, Chittagong 4000, BangladeshPublications
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Research Article
Comparative Anti-dirrhoeal and Antimicrobial Activities of Methanol Extract of Leea indica (Burm. f.) Merr. and Leea macrophylla Roxb. Ex. Hornem (Fam. Vitaceae) and Four Bangladeshi Market Preparations
Author(s): Syed Mohammed Tareq*, Mohammed Ibrahim, Sarrin Shahadat, Mohi Uddin Chowdhury M and Md Jakaria
Both Leea indica and Leea macrophylla are belonging to Leeaceae family. The aim of the present study was to detect different chemical groups of the methanol leaf extract of the plants (L. indica & L. macrophylla) and to compare the anti-diarrheal and antimicrobial activity of these extracts with four established market preparations. Phytochemical screening of extracts of L. indica, L. macrophylla confirmed the presence of alkaloids, glycosides, steroids, tannins, flavonoids, reducing sugars, and gums. In antidiarrheal activity test, the methanol extracts of the L. indica and L. macrophylla at the doses of 500 mg/kg and 250 mg/kg reduced the total number of stool in the mice to a considerable extent as well as increased the latency period in comparison to the control groups and the result was statistically significant but less in extent than market prep.. Read More»
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