KM Priti

Department of Pharmacy, Kailash Institute of Pharmacy and Management, Gorakhpur, India

Publications

• Research Article   
  Formulation and evaluation of Embelin (a phytoconstituent) loaded Phytosome complex
  Author(s): DK Vishwakarma, KM Priti, Sanjay Krishna Pandey* and JN Mishra
  
  Embelin was one of active constituents of Embelia ribes Burm. f. Embelin has been reported to possess many pharmacological effects. The studies was perform to enhance the bioavailability of poorly water soluble embelin, reduce the dose of Embelin, prevent the degradation of Embelin in the GIT. For this, phytosome, a novel drug delivery system, was adopted. Total six Embelin loaded phytosome complex formulations coded as EMBP1, EMBP2, EMBP3, EMBP4, EMBP5 and EMBP6 using soya lecithin and Chitosan in variable ratio were prepared by anti-solvent precipitation method and Rotary evaporation technique. The phytosome was characterized by parameters like percentage yield, particle size determination, entrapment efficiency, scanning electron microscopy (SEM), in vitro release studies and establish drug release kinetic studies. Among six formulations, the Formulation EMBP5 well optimized. EMBP5.. Read More»
  

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