Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Hari Prasad Sonwani
Department of Pharmacology, Apollo College of Pharmacy, Anjora, IndiaPublications
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Review Article
Cardiac Glycoside Poisoning: Pharmacological Therapy
Author(s): Hari Prasad Sonwani*, Pragya Sahu and Rashi Bandey
Because cardiac glycosides are found in natural sources and are widely used in therapeutic settings, they are a significant cause of poisoning. Toxicological manifestations of poisoning can range in intensity. Bradycardia, heart bloc and gastrointestinal symptoms are the main clinical characteristics. Ventricular fibrillation or tachycardia causes death. Numerous treatments have been employed; the most popular ones include activated charcoal, atropine, β-adrenoceptor agonists, magnesium, anti-digoxin Fab and temporary pacing. More unusual treatments include fructose-1,6-diphosphate (which is undergoing a clinical trial) and anticalin. Even with therapies that have been around for decades, there is still disagreement over the best way to use them, when to use them and what dosage would produce the best results. This adds to the variation in use that exists worldwide. Access is ano.. Read More»
DOI: 10.4172/0975-413X.15.6.134-141
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Citations : 15261
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