Fatima Asserne

Laboratory of Molecular Chemistry, Materials and Catalysis, Faculty of Sciences and Technics, Sultan Moulay Slimane University, Be ni-Mellal, BP 523, Morocco

Publications

Research Article
Regioselective synthesis of 1-alkyl-4-nitro-1H-imidazole using 2-methyl-5-nitroimidazole and 4 nitroimidazole as starting reagents
Author(s): Yassine Hakmaoui*, Fatima Asserne, Abderrahim El Haib, Rahhal El Ajlaoui, Said Abouricha and El Mostapha Rakib

In this work, we were able to achieve a total regioselectivity for the alkylation in the N1 position of 2-methyl-5-nitro-1H-imidazole and in the N1 position of 4-nitro-1H-imidazole; it was carried out in different operating condition (base, solvent, temperature…) with different alkylating agents. The structures of the products obtained, they are established by 1H and 13C NMR spectroscopy. In parallel, a computational study it was carried out in accordance with the experimental results obtained (scheme 1). .. Read More»
DOI: 10.4172/0975-413X.14.4.12-16

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