Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Eldhose M J
Department of Pharmacology, Sanjo College of Pharmaceutical Studies, Vellapara, Chithali Palakkad, IndiaPublications
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Review Article
Protein Assembly: An Understanding and Clarification
Author(s): Sivakumar B*, Eldhose M J, Asish S, Vipuldas MK, Anila Kumar and Vidhya PM
Alzheimer's disease is characterized by the accumulation of mis folded proteins that form fibrillary amyloid deposits in specific regions of the central nervous system. This leads to memory loss, changes in personality, abnormal behavior and a decline in cognitive abilities. In the early stages of the disease, individuals may experience short-term memory loss, difficulty remembering names and addresses and an inability to learn new information. As the condition progresses, these changes become more pronounce and individuals may even forget the way to their own home. AD patients often exhibit emotional features such as frustration, irritability and hostility. Genetic factors account for seventy percent of Alzheimer's cases, while environmental factors contribute to twenty-one percent. Late-onset Alzheimer's, which occurs after the age of 60, is the most common form of the disease. Curr.. Read More»
DOI: 10.4172/0975-413X.16.2.239-242
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Citations : 15261
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