Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Dr.shiva kumar
Gitam School of Pharmacy, GITAM Deemed to be University, Hyderabad, Telangana, IndiaPublications
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Research Article
Novel Pyirimidine Carboxamide Derivatives As Potential Anticancer Agents,snthesis And Characterisation
Author(s): Shameem Sultana* and Dr.shiva kumar
Background: Cancer was credited as the second leading cause to global death rate with estimated toll of deaths more than 18 million. Though many anticancer agents are available in the market, there is an essential need to explore novel drug candidates for cancer treatment due to the various adverse effects associated with the current anticancer agents. Pyrimidine scaffold is a ubiquitous heterocyclic system present in important anticancer agents. Current investigation aims to find the newer class of anticancer lead molecules with pyrimidine as the central pharmacophore. Objective: Primary objective of the current research is to evaluate the anti-cancer potential of the novel class of carboxamide functionality tethered pyrimidine derivatives against six different cancer cell lines. Method: Current research designed and synthesized a novel cla.. Read More»
DOI: 10.4172/0975-413X.14.10.34-42
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Citations : 15261
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