Chamundeswari RN

Department of Pharmaceutical Analysis, GIET School of Pharmacy, Rajahmundry-533296, Andhra Pradesh, India

Publications

• Research   
  Spectrometric Estimation of Gliclazide, Nortriptyline, Cilnidipine in Pure and Tablet Dosage Form Using MBTH
  Author(s): Vijayalakshmi R*, Chamundeswari RN, Surya Kumari R and Suhasini S
  
  The objective of the present work is to develop simple, precise and accurate colorimetric methods for the estimation of Gliclazide (Method A), Nortriptyline (Method B), Cilnidipine (Method C) using MBTH (3-Methyl-2-Benzothiaazide Hydrazine) reagent. All the three Methods were developed on Perkin Elmer LAMBDA 25 UV/VIS spectrophotometer with 1cm quartz cells. Quantification of Gliclazide, Nortriptyline, Cilnidipine were done by Oxidative coupling method using MBTH as reagent. Gliclazide (Method A), Nortriptyline (Method B) and Cilnidipine (Method C) undergoes oxidation with ferric chloride and couples with MBTH. The coupled oxidant shows maximum absorbance measured at 660 nm for Gliclazide (Method A), 650 nm for Nortriptyline (Method B), and 600 nm for Cilnidipine (Method C). The colorimetric method was extensively validated as per ICH guidelines and all the parameters were within the .. Read More»
  

  Abstract HTML PDF

30+ Million Readerbase

Google Scholar citation report

Citations : 15261

Der Pharma Chemica received 15261 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons