Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Bagade Shashikant
Department of Pharmaceutical Quality Assurance, SVKMs NMIMS School of Pharmacy and Technology Management, Shirpur, Maharashtra, IndiaPublications
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Review Article
Exploring Hybrid Molecules as Multifunctional Treatments for Alzheimer\'s Disease
Author(s): Nikhil Musale* and Bagade Shashikant
Alzheimer's Disease (AD) is one of the most common health conditions in the world and affect neurons and changes several proteins. Based on the 35.6 million of AD cases reported to the world in 2011, the current clinical single molecule treatment of single drug targets single disease component has not been proved to be effective enough and researchers and practitioners are nowadays working together according to the principle of collaboration and focusing on the necessity of collaboration, in order to give a single molecule to multiple disease processes, that is, to nerve cell death. In recent years’ medicinal chemists have been working together to design along with synthesize hybrid molecules. These molecules represent the optimal composition for generating two pharmacologically usable fragments of two oppositely acting chemical species. Alzheimer's Disease (AD), with a .. Read More»
DOI: 10.4172/0975-413X.17.1.562-569
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Citations : 15261
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