Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Aradhya Dev Srivastav
Department of Chemical Engineering, IET Lucknow-226021, IndiaPublications
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Research Article
Standardization and Hypoglycemic Activity of Hydro-Alcoholic Leaves Extract of Morus Alba
Author(s): Sunita Singh, Aradhya Dev Srivastav, Deepak Singh, Bharat Mishra, Abhishek Kumar Chandra, Sudeep Yadav and Dhananjay Singh*
The aim of this work is to carry out identification of some phytoconstituents of Morus alba which are responsible for antidiabetic activity and their complications as well as antioxidant activity. Phenolic compounds and flavonoidal compounds were estimated in the various extracts (chloroform, petroleum ether, ethanol and water). Phenolic compounds are determined by using a linear standard curve of gallic acid (y = 0.0025x+ 0.0334, R2 =0.9997) and found to be higher in water extract (67.32±0.50 mg/g GAE) in comparison to other extracts. Flavonoidal compounds estimated through a linear standard curve of quercetin (y=0.004x+ 0.0431, R2 =0.9985) and found to be higher in water extract (55.37±0.05 mg/g QE) than other extracts. HPLC was used for the determination of quantities of phytoconstituents present in M. alba. Chromatogram of HPLC shows the presence of qu.. Read More»
DOI: 10.4172/0975-413X.14.5.1-15
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