Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Anil B Chidrawar
P.G. Department of Chemistry, Degloor College, Degloor-431717, S.R.T.M.U, Nanded, Maharashtra, IndiaPublications
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Research Article
Antifungal Activity of Condensed Benzothiazole and Its Derivatives
Author(s): Anil B Chidrawar*
A simple and efficient method have been used for the synthesis of 2-substituted derivatives of 3-cyano-4,14-diimino-2-methylthio-10-nitropyrimido [2,3-b] pyrazolo [3,4-e] pyrimido [2,3-b] [1,3] benzothiazole have been prepared through one Step Multicomponent reaction by heating a mixture of 3-amino-4-imino-8-nitro-2H-pyrazolo[3,4-e]pyrimido[2,3-b][1,3]benzothiazole and bis (methylthio) methylene malononitrile independently with aromatic amines/phenols/heterylamines/compounds containing active methylene group respectively in the presence of dimethyl formamide and catalytic amount of anhydrous potassium carbonate. All these newly synthesized compounds were screened for anticancer activity... Read More»
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