Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Ali M Hassan
Department of Chemistry, Faculty of Science, Al -Azhar University, EgyptPublications
-
Research Article
Microwave-Assisted One-Pot Synthesis of Novel Polyarylpyrrole Derivatives of Expected Anticancer Activity
Author(s): Ahmed Younis*, Ali M Hassan, Mohamed F Mady, El-Haddad AF, YassinFA and Mahmoud Fayad
An efficient synthesis of Novel pyrrolederivatives was achieved via solventless reaction of chalcones 1(a-e) with different aldehydes 2(a-e) and ammonium acetate in the presence of sodium cyanide in one-pot under microwave irradiation. The notable features are short reaction time, high yield and purification of product by non-chromatographic methods, i.e., by simple recrystalization compared to the classical condition. Some of the synthesized compounds were evaluated against HepG-2, and showed significant antitumor activities... Read More»
Select your language of interest to view the total content in your interested language
Google Scholar citation report
Citations : 15261
Der Pharma Chemica received 15261 citations as per Google Scholar report
Der Pharma Chemica peer review process verified at publons
