Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Abstract
The new Cu(II) and Ni(II) complexes of schiff bases: Synthesis, characterization and antibacterial studies
Author(s): K. Babu* and P. AmuthaWe synthesized new schiff bases by the reaction between methyl substituted o-phenylenediamine, 2-OHnaphthaldehyde and isatin. The obtained schiff bases were treated with metal acetates in ethanol medium afforded corresponding metal complexes and these were characterized with help of melting point, molar conductance, UVVis, IR, 1HNMR and 13CNMR spectroscopic techniques. Antibacterial activities of newly synthesized compounds were carried out against E. coli (gram negative) and S. aureus (gram positive) bacteria. The transition metal complexes showed good antibacterial activity than the free ligand against selective bacteria were reported.
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