Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
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Abstract
The antibacterial activity of substituted 4-(hydroxymethyl)-5,5-dimethyl- 2,5-dihydro-2-oxofurans
Author(s): Gayane G. Tokmajyan, Lusine V. Karapetyan*, Rima V. Paronikyan and Hrachya M. StepanyanThe antibacterial activities of 4-(hydroxymethyl)-5,5-dimethyl-2,5-dihydro-2-oxofuran derivatives have been evaluated. They exhibited high antibacterial activities in vitro and in vivo. These compounds, especially compound 1, definitely exceeded norsulfazole and furazolidone in case of study in vitro. They had analogous advantage in respect of norsulfazole during the study in vivo.
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