Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
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Abstract
Tamarind Juice Catalyzed Green and Efficient Synthesis of Biscoumarin Derivatives in Aqueous Media
Author(s): Amit S Waghmare*, Ramrao A Mane, Vinod T Kamble and Bhaskar S DawaneA green and efficient synthesis of biscoumarin derivatives is achieved in aqueous media catalyzed by tamarind juice as a natural catalyst. This Knoevenageal condensation is achieved using 4-hydroxycoumarin and different aromatic aldehyde in aqueous media at reflux condition. The present protocol avoids the use of hazardous reagents and toxic solvents. One-pot condensation, shorter reaction times, high yields, operational simplicity, simple workup procedure are some of the additional features of this protocol.
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Citations : 15261
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