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Synthesis, physical characterization, and biological activity of some Schiff base derive from substituted aniline and it's complexes with (Co, Ni) transition metal ion's | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

Synthesis, physical characterization, and biological activity of some Schiff base derive from substituted aniline and it's complexes with (Co, Ni) transition metal ion's

Author(s): Hanaa Hameed Haddad and Hussein NaserHammadi

HugoSchiff describes the condensation between an aldehyde and an amine leading to a Schiff base in 1864[1] , metal ion's through imine nitrogen and other groups usually linked to the aldehyde [2], N,S and O donor atoms show broad biological activity and are special interest due to of the variety of way in which they are bonded metal ion's[3] , Schiff base derived from aromatic amines and aromatic aldehyde have a wide variety of application in many field biological , inorganic and analytical chemistry [4,5], because of their ability to act as didentate ligands for transition metal ion's [6], they have recently received considerable attention due tois good performanticin coordination chemistry [7], unique antibacterial , anticancer and other physical activities [8], in this work we wish to report synthesis and characterization a thermodynamic behaviors of such class of new ligands having ( C=N ) and ( OH ) groups toward its probable color , reaction and stabilities with ( Co , Ni ) metal ion's using spectrophotometric analysis in different temperature.


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