Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
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Abstract
Synthesis of 1-amidoalkyl-2-naphthols by a three component reaction catalyzed by methane sulphonic acid
Author(s): V. Jhansi Rani, M. Suresh, P. Lavanya, K. Veena Vani, B. Nagarjuna and C. Venkata RaoA three component one-pot condensation of 2-naphthol, ureas/amides and aldehydes catalyzed by methane sulphonic acid, under ambient conditions to afford 1-amidoalkyl-2-naphthols in excellent yields, with short reaction time, simple procedure, easy work-up and ecofriendly reaction condition.
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