This research includes synthesis of some new heterocyclic derivatives of 5-Nitroisatin namely 5-Nitro-3-(Ethyl imino acetate)-2-oxo indole (1), 5-Nitro-3-[(imino Aceto) urea]-2-oxo indole (2), 5-Nitro-3-[(imino Aceto)thiourea]-2-oxo indole (3), and 5-Nitro-3-[(imino Aceto) phenylthiourea]-2-oxo indole (4), and characterized by Fourier-transform infrared (FTIR) spectroscopy, Proton nuclear magnetic resonance (1H-NMR) and some physical properties. Theoretically, the inhibition efficiency parameters with physical properties were calculated to ensure for possibility using these compounds as inhibitors. Experimentally, studying the chosen compound of the corrosion inhibition efficiency for carbon steel in 3.5% NaCl solution by isatin derivative is chosen theoretically as the best inhibitor using potentiodynamic polarization.
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