Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Abstract
Synthesis, characterization, antibacterial activity and DNA cleavage studies of Schiff base Co(II) transition metal complexes
Author(s): D. Sathis Kumar and A. K. Ibrahim Sheriff *Two Schiff base ligands L 1 and L 2 were obtained by the condensation of o-phenylenedi amine with p- methylbenzaldehyde and p-methoxybenzaldehyde respec tively. Their complexes with Co(II) were prepared a nd characterized by elemental analyses, molar conducta nce, magnetic susceptibility, IR, UV-Vis spectra, N MR, Mass spectral studies, thermal behaviour and Powder X-ra y diffraction studies have also been carried out. T he IR data demonstrate the bidentate coordination of L 1 and L 2 . The XRD data show that Co(II) complexes with L 1 and L 2 have the crystallite sizes of 70 and 72 nm respectively. The DNA cleavage activities of the Schiff base and its complexes were monitored by agarose gel electrophoresis metho d in the presence of hydrogen peroxide and the anti bacterial activities of the ligand and complexes have also be en carried out
Select your language of interest to view the total content in your interested language
Google Scholar citation report
Citations : 15261
Der Pharma Chemica received 15261 citations as per Google Scholar report
Der Pharma Chemica peer review process verified at publons
