Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
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Abstract
Synthesis Characterization and antitumor activity of thiazole derivatives containing indole moiety bearing-tetrazole
Author(s): S. Muralikrishna, P. Raveendrareddy, L. K. Ravindranath, S. Harikrishna and P. Jagadeeswara RaoSchiff base synthesis of thiazole derivatives containing Indole moiety bearing tetrazole ring were synthesised by the condensation of 2-(3-(3chloro -1-(4-substitued phenyl )-tetrazole -2-yl(1H-Indole –yl Aceto hydrazone with potassium thio cyanide and substituted ketones.To this reaction was subjected in schiff base reaction .The structure of these newly synthesized compounds were characterised by 1H NMR,13CNMR ,Mass ,IR, and elemental analysis.
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