Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
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Abstract
Synthesis, Characterization and Antimicrobial Activity Studies of Novel Pyrazole Derivatives
Author(s): Kishan N, Renuka N, Ajay Kumar K, Jayadevappa HPAn efficient and accessible procedure for the synthesis of substituted pyrazoles was described. The method involves cyclocondensation reaction of chalcones with 2,4-dimethylphenylhydrazine hydrochloride in the presence of catalytic amount of hydrochloric acid to obtain pyrazole derivatives in good yields. The synthesized new compounds were characterized by spectral studies and elemental analysis; and evaluated in vitro for their antimicrobial susceptibilities.
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Citations : 15261
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