Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Abstract
Synthesis, Biological Evaluation of 4-aminoquinoline 1, 2, 4-triazole Conjugated Benzothiazole as Potent Analgesic, Anti-inflammatory
Author(s): Anjali Thakur, Pusphraj S GuptaIn this study the synthesis of novel 4-aminoquinoline 1,2,4-triazole derivatives containing benzothiazole (4a-4j and 5a-5j) done by three major steps and characterization of synthesized derivatives assigned by Infra-Red (IR), Proton Nuclear Magnetic Resonance (1H-NMR), Mass Spectra (MS), Carbon-13 Nuclear Magnetic Resonance (13C-NMR). The biological evaluation for in vivo analgesic and anti-inflammatory activity was performed for primed derivatives, among the tested compounds 5a, 5c, 5e, 5g, 5h, 5i showed more potent anti-inflammatory and 4i, 5a, 5b, 5f, 5g, 5h showed analgesic activity compared standard drug meloxicam and diclofenac sodium.
Select your language of interest to view the total content in your interested language
Google Scholar citation report
Citations : 15261
Der Pharma Chemica received 15261 citations as per Google Scholar report
Der Pharma Chemica peer review process verified at publons
