Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Abstract
Synthesis and Study of Biological Active S-triazines
Author(s): Noosrat Kortiwala, Jitesh Patel, Vikas DesaiSome novel s-triazines were synthesized in laboratory by substituting the cyanuric choloride, with 1-[2-amino-1-(4-methoxyphenyl)ethyl]cyclohexanol, aryl flouro amines, aryl ureas and aryl amines, The structure of synthesized s-triazines was determined by IR and NMR spectra. The synthesized compounds showed potential biological activity against the bacterial strains, out of which compounds 6-2b, 6-7b and 6-10b showed good activity against E. coli and 6-8b against Klebsiella pneumoniae and 6-4b against Staphylococcus auerus whereas 6-2b, 6-4b and 6-7b are most active against Aspergillus clavatus and Aspergillus niger and 6-1b, 6-8b and 6-9b are most active against Candida albicans fungal strains
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