GET THE APP

Synthesis and Larvicidal Activity of Morpholinophenyl and Benzyl-Fluoro Pyrimidine Derivatives | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Synthesis and Larvicidal Activity of Morpholinophenyl and Benzyl-Fluoro Pyrimidine Derivatives

Author(s): Satya Kumar Avula, Shashi Kanth Boddu and Prashanthi Yarasani*

A series of 5-fluoro-N4-(3-(4-substitutedbenzylamino)phenyl)-N2-(4-morpholinophenyl) pyrimidine-2,4-diamine derivatives 7a-J were prepared and tested for their larvicidal activity against third instar larvae at 24, 48 and 72 hours and values were compared with Malathion as a positive control. Compounds 7a, 7c, 7f, 7g and 7i exhibited good larvicidal significant activity. Interestingly, compounds 7b, 7d, 7e, and 7h showed excellent activity very likely due to the presence of functional groups attached to the benzyl ring.


Full-Text PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 15261

Der Pharma Chemica received 15261 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry