Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
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Abstract
Synthesis and characterization of some novel isoxazoles via chalcone intermediates
Author(s): Kapubalu Suneel Kumar, Kovvuri Tatendra Reddy, Appikonda Vamsikanth, Gudaparthi Omprakash, P. K. DubeyThe synthesis and characterization of some novel isoxazoles derivatives have been presented. Acylation of resorcinol followed by nuclear prenylation with isoprene gives Chroman. Chroman on treatment with p-substituted benzaldehydes affords substituted chalcones. Isoxazoles have been prepared from chalcones by treating with hydroxylamine hydrochloride. The structure of isoxazoles has been characterized by spectral analysis.
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