Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Abstract
Synthesis and characterization of (novel heterocyclic) 3-amino-9-ethyl carbazole dithiocarbamate [AECZDTC] ligand and its metal complexes
Author(s): K. Venugopal, K. Rameshbabu and J. SreeramuluThe growing interest in the chemistry of sulphur donor ligands are due to their encouraging anticancer, antibacterial and antifungal activities as well as their widespread industrial application. Dithiocarbamates belong to this class and much attention has been paid to them. A New series of bidentate ligand dithocarbamate of 3-amino- 9-ethyl carbazole dithiocarbamate (AECZDTC) Ligand and its Metal complexes (AECZDTC) have been synthesized by new synthetic methods as it’s sodium salt. In the reaction of Copper Chloride and Ruthenium Chloride with the AECZDTC corresponding complexes were prepared. The complexes were characterized by elemental analysis, IR, 1H NMR, UV, ESR, TGA – DTA and conductometric titrations. In addition the authors have been screened the compounds for biological activity of Cu, Ru complexes. It was found that the compounds have shown activity against bacteria.
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