Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.
Abstract
Synthesis and biological activity of novel substituted N-(1-methylpiperidin-4yl)-2-(arylsulfonyl)-1H-indol-4-yl-amines as 5-HT6 receptor ligands
Author(s): Jagadish Babu Konda, Ramakrishna V. S. Nirogi, Anil K. Shinde,Kiran Kumar Kandukuri, K. R. Sastry and P. K. DubeyA novel series of N-(1-methylpiperidin-4-yl)-2-(arylsulfonyl)-1H-indol-4-yl-amines was designed and synthesized as potential 5-HT6 receptor ligands and tested for human 5-HT6 receptor binding affinities. All the tested compounds showed moderate to high binding affinities towards 5-HT6 receptor. The most potent compound 11b was selected as a hit which can be further optimized to get the potential 5-HT6 receptor ligands.
Select your language of interest to view the total content in your interested language
Google Scholar citation report
Citations : 15261
Der Pharma Chemica received 15261 citations as per Google Scholar report
Der Pharma Chemica peer review process verified at publons
