Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Abstract
Synthesis and Antimicrobial Screening of Novel Tetrazolo Triazolo Substituted Mercapto Quinoxalines
Author(s): Srinivas B, Prasanna B and Ravinder M*A novel and convenient synthesis of substituted 6-(substituted thio) tetrazolo[1,5-a] triazolo[3,4-c] quinoxalines has been carried out. The newly synthesized compounds have been characterized by IR, 1HNMR, and mass spectral data followed by elemental analysis. All the newly synthesized heterocycles have been screened for their in vitro anti-microbial activity against Staphylococcus aureus and Bacillus subtilis as Gram-positive bacteria, Escherichia coli and Pseudomonas aeruginosa as Gram-negative bacteria. They were also evaluated for their in vitro anti-fungal potential against Candida albicans. Few of them have exhibited the promising activity.
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Citations : 15261
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