Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Abstract
Stability indicating nature of RP-HPLC method for determination of impurity profile in malathion
Author(s): Veera Reddy. Arava, Madhusudhan Reddy. Bethi, Kameshwar Rao. Cherukuri, Gopichand. Thota and Sanjeeva Reddy.Cherukupally.The objective of the present work was to develop stability indicating RP-HPLC method for determination of impurities in Malathion on YMC-Pack ODS AQ 250 X 4.6mm 5μm column using a gradient mixture of solvent A ( Milli Q water, adjust the pH of the above solution to 2.5 using Orthophosphoric acid) and solvent B (Methanol). The flow rate is 0.7ml/min and the detection wavelength is 210nm. Statistical analysis proved the method to repeatable, specific and accurate for estimation of Malathion and its impurities. It can be used as a stability indicating method due to its effective separation of the drug from its impurities.
Select your language of interest to view the total content in your interested language
Google Scholar citation report
Citations : 15261
Der Pharma Chemica received 15261 citations as per Google Scholar report
Der Pharma Chemica peer review process verified at publons
