Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
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Abstract
Simple and efficient method for the preparation of novel tetrazole derivatives spectral characterization and its antibacterial activities
Author(s): Govindan Shanmugam, Selvam Elavarasan, Bhakiaraj and Mannathuswamy GopalakrishnanNovel tetrazole analogues with bio-active cores have been synthesized by a simple synthetic methodology. The synthesized compounds are characterized using FT-IR, MS, 1H, 13C and HSQC NMR spectroscopic techniques. The synthesized compounds also screened for their antibacterial activities against Staphylococcus aureus, Escherichia coli, Vibreo cholerae, Pseudomonas aeruginosa and Klebsiella pneumonia. The synthesized compounds are showing very good activities against all the tested bacterial strains.
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Citations : 15261
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