Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.
Abstract
SbCl3-HAP catalyzed aza-Michael addition of aliphatic amines to �Ž�±,�Ž�² -unsaturated carbonyl compounds and nitriles
Author(s): Rajni Khajuria, Raj Kumar, Deepali Mahajan,* and Kamal K. KapoorAn efficient aza-Michael addition of aliphatic amines (primary and secondary) to a series of α,β-unsaturated carbonyl compounds and nitriles has been carried out using antimony (III) chloride supported over hydroxyapetite (SbCl3-HAP) as an effective catalyst in acetonitrile to produce the corresponding β-amino derivatives in high yields. The method is simple, general and offers limited chemoselectivity, as aromatic amines were found to be unreactive.
Select your language of interest to view the total content in your interested language
Google Scholar citation report
Citations : 15261
Der Pharma Chemica received 15261 citations as per Google Scholar report
Der Pharma Chemica peer review process verified at publons
