Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Abstract
RP-HPLC Method Development and Validation for Pioglitazone in Bulk and Marketed Formulation
Author(s): Meenaxi M. Maste*, Nikhil S. Gawas, Utkarsh Shashtri and Poonam ShelarThe work describes a precise, accurate and reproducible Reverse Phase High Performance Liquid Chromatographic (RP-HPLC) method for development and validation of Pioglitazone in tablet dosage form on Lachrome Liquid chromatographic system having PDA-20 A UV/VIS Detector using stationary phase C18 column (300 mm × 3.9 mm, 5 μm, particle size) and acetonitrile:phosphate buffer, (50:50 v/v) as mobile phase at flow rate of 1.00 ml/min and the detection wavelength was 267 nm. The retention time for Pioglitazone was found to be 8.08 min. The method was validated for precision, accuracy, linearity range, robustness, system stability, as per ICH guidelines Q2(R1).
Select your language of interest to view the total content in your interested language
Google Scholar citation report
Citations : 15261
Der Pharma Chemica received 15261 citations as per Google Scholar report
Der Pharma Chemica peer review process verified at publons
