Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Abstract
Review on Pyridine Analogues as Anti-Microbial, Anti-TB and Anti-oxidant Activity
Author(s): Asim Vankar, Harshad Solanki, Amisha Ladumor, Utkarsh Patil* and Dr. Sabir Khan PathanPyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus, descriptions of these new ligands and their applications abound each year. Tuberculosis (TB), a disease caused mainly by the Mycobacterium tuberculosis (Mtb), is according to the World Health Organization (WHO) the infectious disease responsible for the highest number of deaths worldwide. A series of pyridine derivatives were designed and synthesized as new anti-Mycobacterium tuberculosis agents. Anti-Microbial testing towards selected gram-negative bacteria, gram positive and fungi. The Anti-Bacterial activities of 4 & 7 analogues compared with different standard drugs. The objective pf this review article is to analyse different properties of Pyridine analogues.
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