Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.
Abstract
Novel synthesis of 4-amino-2-hydroxymethyl-1-butanol and its purine analogues
Author(s): Vascuri Janardhana Rao, Rama Shankar, Khagga Mukkanti and N. A. VekariyaNovel and improved synthesis of Famciclovir drug substance through N-(2-amino-4-chloro-6-[[4-hydroxy-3- (hydroxymethyl)butyl]amino]pyrimidin-5-yl)formamide from 4-amino-2-hydroxymethyl-1-butanol and N-(2-Amino- 4,6-dichloro-5-pyrimidinyl)formamide. Further this synthetic method involves the 2-acetoxymethyl-4-azido-1-butyl acetate and 4-azido-2-hydroxymethyl-1-butanol as novel intermediates in the preparation of 4-amino-2- hydroxymethyl-1-butanol.
Select your language of interest to view the total content in your interested language
Google Scholar citation report
Citations : 15261
Der Pharma Chemica received 15261 citations as per Google Scholar report
Der Pharma Chemica peer review process verified at publons
