Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
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Abstract
L-tyrosine catalyzed Knoevenagel condensation: Facile synthesis of cyanoacrylonitriles cyanoacrylates and cyanoacrylamides in solvent free condition under grindstone method.
Author(s): G. Thirupathi, M. Venkatanarayana, P. K. Dubey and Y. Bharathi KumariL-tyrosine has been utilized as an efficient catalyst for the Knoevenagel condensation of arylaldehydes with active methylene compounds such as malononitrile, ethylcyanoacetate and cyanoacetamide in solvent free condition under grindstone method at room temperature to afford cyanoacrylonitriles, cyanoacrylates and cyanoacrylamides.
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Citations : 15261
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