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Kinetics and mechanism of oxidation of p-nitrobenzaldehyde by potassium bromate in perchloric acid medium | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

Kinetics and mechanism of oxidation of p-nitrobenzaldehyde by potassium bromate in perchloric acid medium

Author(s): Anshul K. Jain, Meena and Dinesh Kumar

Oxidation of aromatic aldehydes has been studied by several workers. Aromatic aldehydes found to have wide applications in synthetic and pharmaceutical industries. Benzaldehydes are used as flavoring agents, in perfumes, in the manufacture of triphenylmethane dyes such as malachite green etc. and in the synthetic chemistry in the synthesis of other aromatic aldehydes and α,β unsaturated acids. Richard have studied and bacterial activity and found that these compounds are being used to preservatives in ophthalmic solutions. Due to their synthetic importance several workers have made attempts to study these compounds by different oxidants. Ketrolac, an analgesic and anti-inflammatory agent is equal to morphine sulphate on a weight to weight basis for the alleviation of post operative pain. Atorvastatin and Rosuvastatin calcium lowers the cholesterol levels. Both are synthesized from aromatic aldehyde (p-Fluorobenzaldehyde). In the light of above back ground, we will try to study kinetics and mechanism of proposed reactions of oxidation of benzaldehyde and substituted benzaldehydes by potassium bromate in acidic medium.


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