Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Abstract
Isolation, identification, antioxidant, antibacterial and anticancer activity of new complex between isolated alkaloid from Haloxylon. Sp and soybean
Author(s): Iqbal J. B. AlassadiGenistein, daidzein, glycitein and quercetin are flavonoids present in soybean and other vegetables in high amounts. These flavonoids can be metabolically converted to more active forms, which may react with guanine in the DNA to form complexes and can lead to DN depurination. New complex were synthesized between alkaloid isolated from Haloxylon,SP plant.& syobin. The complex &alkaloid was characterized by IR , Spectra ,& TLC. The compounds were screened in vitro for antibacterial activity by inhibition activity against Staphylococcus aureus &Escherichia coli bacteria . and the cytotoxicity assay against the human red blood cells. The result of in vitro study for Rhabdomyosarcoma cell growth assay has shown that the alkaloid isolated had more cytotoxic inhibition after 24,48 & 72 hours .
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Citations : 15261
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