Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Abstract
Isolation, Characterization and Antibacterial Activity of Lanostane Triterpenoid from the Leaves of Stachyterpheta jamaicensis Linn Vahl
Author(s): Donatus Ebere Okwu, Offiong N. OhenhenChemical investigation of the bioactive constituents from the leaves of Stachytarpheta jamaicensis Linn Vahl (Gervao, Brazilian tea or Bastard vervain) resulted in the isolation of a new lanostane phenylacetate (1,3,16β-yl-phenypropylacetate-lanostan-5,11,14,16,23,25- hexen-22-one). The structure was elucidated using NMR spectroscopy in combination with IR and MS spectral data. The isolated compound inhibited Streptococcus fecalis, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. This result supports the use of Stachyterpheta jamaicensis in phytomedicine for the treatment of cough, burns, gonorrhea, asthma, boils, sores, burns and healing of wounds in herbal medicine in Nigeria
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