Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Abstract
In-Vitro Antidiabetic Activity of Launaea procumbens Extracts
Author(s): Indirabai M.B*, Pujari N, Madagi S.B and Hoskeri HMedicinal plants have gained broad range of attention in recent years for their vital pharmacological properties. Launaea procumbens is one among the potential medicinal plants traditionally used for the treatment of several diseases. With increase in the growth rate of diabetic patients and also with pronounced side effects of already available treatments, search for medicines from natural sources is always a matter of interest for researchers. Therefore in current study, methanol and ethyl acetate extracts of L. procumbens were studied for anti-diabetic potential through in-vitro approach. In this study, in-vitro amylase inhibition assay and glucose uptake assay were carried out. Results are reported in a dose dependent inhibition of α-amylase in methanol extract. Whereas yeast cells showed significant increase in inhibition of glucose uptake in methanol extracts of L. procumbens. Hence the anti-diabetic activity was prominently seen in methanol extract of L. procumbens, therefore the study can be of great interest in further exploring of anti-diabetic activity of L. procumbens by in-vivo and in-silicon approaches.
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Citations : 25868
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