Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Abstract
Evaluations of protoscolicidal activity of Cardamom extract against hydatid cyst protoscoleces
Author(s): Hormoz Mahmoudvand, Sedigheh Nadri, Sareh Jahanbakhsh and Mehdi RezaeifarThe present study aims to evaluate the scolicidal effects of Elettaria cardamomum L. (cardamom) extract on the protoscoleces of hydatid cysts on an in vitro model. Protoscoleces were aseptically aspirated from the livers of naturally infected sheep. Various concentrations of extract were used for 10-60 minutes. Eosin exclusion test was used to determine the viability of protoscoleces. Findings showed that extract at the concentrations of 200 and 100 mg/mL killed 100% protoscoleces after 10 and 20 minutes of exposure, respectively. Obtained results in this investigation for the first time demonstrated that cardamom might be a natural source for the production of new scolicidal agents
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Citations : 15261
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