GET THE APP

Enzyme activities of Nile tilapia (Oreochromis niloticus) during lethal and sublethal exposure to cypermethrin | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Enzyme activities of Nile tilapia (Oreochromis niloticus) during lethal and sublethal exposure to cypermethrin

Author(s): Bangeppagari Manjunatha, Juan Ortiz Tirado, Patricia Falconí Salas, Darwin Rueda Ortiz, Gooty Jaffer Mohiddin, G. Venkata Subba Reddy3, Maddela Naga Raju, Mariadoss Selvanayagam

The present study was designed to compare the responses in three different tissues (gill, liver and muscle of freshwater fish, Nile tilapia (Oreochromis niloticus) exposed to a synthetic pyrethroid, cypermethrin. Fish were exposed to lethal concentration (7.5 μg/L) for 2, 5, 7 and 9 days and, sublethal concentration (1.5 μg/L) for 7, 14, 21 and 28 days, and the alterations observe the enzyme activity levels were determined. Aspartate aminotransferase (AST), alanine aminotransferase (ALT) and glutamate dehydrogenase (GDH) activities were increased in all the tissues with an increase in the time of exposure. However, under sublethal concentration of cypermethrin for 14, 21 and 28 days, a decreasing tendency was observed in all the three tissues. The tissue damage specially the liver and muscles are responsible for the increased level of amino transfereae in Oreochromis niloticus. Hence, the increased level of enzymes could be used as an effective biomarker in cypermethrin exposed and which is also concentration dependent.


Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 15261

Der Pharma Chemica received 15261 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry