Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
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Abstract
Efficient Synthesis of 3-(phenyl sulfonyl)-2H-Chromen-2-one
Author(s): R. V. Kupwade*Herein enviro-economic protocol for the synthesis of 3-phenylsulfonyl coumarins using THAM as a commercially available catalyst has been reported. Decent yields and easy isolation of the products avoiding conventional isolation as well as purification methods are the noteworthy merits of the developed protocol. The most fascinating and significant finding regarding driving force in the synthesis of phenylsulfonyl coumarins through Knoevenagel condensation reaction has also been disclosed.
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Citations : 15261
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