GET THE APP

Design, synthesis, characterization and bioassay of novel amide derivatives of 2-(benzo[d]thiazol-2-yl)phenol | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Design, synthesis, characterization and bioassay of novel amide derivatives of 2-(benzo[d]thiazol-2-yl)phenol

Author(s): Sreedhar B., Veera Reddy T., Naga Raju C., Padmavathi V. and Vidya Sagar Reddy G.

A series of new carboxamide derivatives of 3-(2-(benzo[d]thiazol-2-yl)phenoxy)propanoic acid (2) were synthesized by the reaction of 3-(2-(benzo[d]thiazol-2-yl)phenoxy)propanoyl chloride (3) with various bio-potent amines by using 1-methylimidazole as an acid scavenger via Schotten-Baumann reaction. The newly synthesized compounds were characterized by IR, NMR and mass spectral analysis. The title compounds were evaluated for their efficacy as antibacterial and antifungal agents in vitro. Compounds 4e-h showed high inhibitory activity against both bacteria and fungi.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 15261

Der Pharma Chemica received 15261 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry