Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.
Abstract
Cytotoxic polyacetylenes and 5-hydroxymethylfurfural from the rhizomes of Panax stipuleanatus
Author(s): Nguyen Quang Tuyen, Pham Thi Thu Ha, Le Thi Phuong Hoa and Dang Ngoc Quang,Phytochemical study on the hexane and butanol extracts of the rhizomes of Vietnamese Panax stipuleanatus has led to the isolation and structural elucidation of three compounds. Two of which are polyacetylenes named stipudiol (1) and panaxytriol (2). The other is characterised as 5-Hydroxymethylfurfural (3). Their structures were determined by a combination of HR-MS and 2D NMR spectroscopy. In addition, all three compounds 1-3 have cytotoxicity against KB cell line. Especially, compound 1 has the strongest ones (IC50 value of 8.11 mg/mL).
Select your language of interest to view the total content in your interested language
Google Scholar citation report
Citations : 25868
Der Pharma Chemica received 25868 citations as per Google Scholar report
Der Pharma Chemica peer review process verified at publons
DOWNLOADS
