Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
Abstract
Coumarins: Biological activity and SAR studies
Author(s): Sohair L. El-Ansary, Doaa E. Abdel Rahman and Nehad M. A. EldydamonyOver the past decades, literature survey revealed that, many naturally occurring and synthetic coumarin derivatives have been discovered and biologically evaluated for a broad range and diverse biological activities. This review provides a systematic summary and insight of the whole range of medicinal chemistry in the current developments of coumarin compounds and some overview on photochemotharpy, linear (psoralen) and angular (angelicin) furocoumarins and structure-activity relationships are also discussed. The perspectives of the future development of coumarin based medicinal chemistry are also presented.
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Citations : 15261
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